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Jul 9

Sound reconstruction from human brain activity via a generative model with brain-like auditory features

The successful reconstruction of perceptual experiences from human brain activity has provided insights into the neural representations of sensory experiences. However, reconstructing arbitrary sounds has been avoided due to the complexity of temporal sequences in sounds and the limited resolution of neuroimaging modalities. To overcome these challenges, leveraging the hierarchical nature of brain auditory processing could provide a path toward reconstructing arbitrary sounds. Previous studies have indicated a hierarchical homology between the human auditory system and deep neural network (DNN) models. Furthermore, advancements in audio-generative models enable to transform compressed representations back into high-resolution sounds. In this study, we introduce a novel sound reconstruction method that combines brain decoding of auditory features with an audio-generative model. Using fMRI responses to natural sounds, we found that the hierarchical sound features of a DNN model could be better decoded than spectrotemporal features. We then reconstructed the sound using an audio transformer that disentangled compressed temporal information in the decoded DNN features. Our method shows unconstrained sounds reconstruction capturing sound perceptual contents and quality and generalizability by reconstructing sound categories not included in the training dataset. Reconstructions from different auditory regions remain similar to actual sounds, highlighting the distributed nature of auditory representations. To see whether the reconstructions mirrored actual subjective perceptual experiences, we performed an experiment involving selective auditory attention to one of overlapping sounds. The results tended to resemble the attended sound than the unattended. These findings demonstrate that our proposed model provides a means to externalize experienced auditory contents from human brain activity.

  • 4 authors
·
Jun 19, 2023

Frequency-Specific Neural Response and Cross-Correlation Analysis of Envelope Following Responses to Native Speech and Music Using Multichannel EEG Signals: A Case Study

Although native speech and music envelope following responses (EFRs) play a crucial role in auditory processing and cognition, their frequency profile, such as the dominating frequency and spectral coherence, is largely unknown. We have assumed that the auditory pathway - which transmits envelope components of speech and music to the scalp through time-varying neurophysiological processes - is a linear time-varying system, with the envelope and the multi-channel EEG responses as excitation and response, respectively. This paper investigates the transfer function of this system through two analytical techniques - time-averaged spectral responses and cross-spectral density - in the frequency domain at four different positions of the human scalp. Our findings suggest that alpha (8-11 Hz), lower gamma (53-56 Hz), and higher gamma (78-81 Hz) bands are the peak responses of the system. These frequently appearing dominant frequency responses may be the key components of familiar speech perception, maintaining attention, binding acoustic features, and memory processing. The cross-spectral density, which reflects the spatial neural coherence of the human brain, shows that 10-13 Hz, 27-29 Hz, and 62-64 Hz are common for all channel pairs. As neural coherences are frequently observed in these frequencies among native participants, we suggest that these distributed neural processes are also dominant in native speech and music perception.

  • 4 authors
·
Jul 7, 2025

Audio-Language Models for Audio-Centric Tasks: A survey

Audio-Language Models (ALMs), which are trained on audio-text data, focus on the processing, understanding, and reasoning of sounds. Unlike traditional supervised learning approaches learning from predefined labels, ALMs utilize natural language as a supervision signal, which is more suitable for describing complex real-world audio recordings. ALMs demonstrate strong zero-shot capabilities and can be flexibly adapted to diverse downstream tasks. These strengths not only enhance the accuracy and generalization of audio processing tasks but also promote the development of models that more closely resemble human auditory perception and comprehension. Recent advances in ALMs have positioned them at the forefront of computer audition research, inspiring a surge of efforts to advance ALM technologies. Despite rapid progress in the field of ALMs, there is still a notable lack of systematic surveys that comprehensively organize and analyze developments. In this paper, we present a comprehensive review of ALMs with a focus on general audio tasks, aiming to fill this gap by providing a structured and holistic overview of ALMs. Specifically, we cover: (1) the background of computer audition and audio-language models; (2) the foundational aspects of ALMs, including prevalent network architectures, training objectives, and evaluation methods; (3) foundational pre-training and audio-language pre-training approaches; (4) task-specific fine-tuning, multi-task tuning and agent systems for downstream applications; (5) datasets and benchmarks; and (6) current challenges and future directions. Our review provides a clear technical roadmap for researchers to understand the development and future trends of existing technologies, offering valuable references for implementation in real-world scenarios.

  • 5 authors
·
Jan 25, 2025

NeuroBOLT: Resting-state EEG-to-fMRI Synthesis with Multi-dimensional Feature Mapping

Functional magnetic resonance imaging (fMRI) is an indispensable tool in modern neuroscience, providing a non-invasive window into whole-brain dynamics at millimeter-scale spatial resolution. However, fMRI is constrained by issues such as high operation costs and immobility. With the rapid advancements in cross-modality synthesis and brain decoding, the use of deep neural networks has emerged as a promising solution for inferring whole-brain, high-resolution fMRI features directly from electroencephalography (EEG), a more widely accessible and portable neuroimaging modality. Nonetheless, the complex projection from neural activity to fMRI hemodynamic responses and the spatial ambiguity of EEG pose substantial challenges both in modeling and interpretability. Relatively few studies to date have developed approaches for EEG-fMRI translation, and although they have made significant strides, the inference of fMRI signals in a given study has been limited to a small set of brain areas and to a single condition (i.e., either resting-state or a specific task). The capability to predict fMRI signals in other brain areas, as well as to generalize across conditions, remain critical gaps in the field. To tackle these challenges, we introduce a novel and generalizable framework: NeuroBOLT, i.e., Neuro-to-BOLD Transformer, which leverages multi-dimensional representation learning from temporal, spatial, and spectral domains to translate raw EEG data to the corresponding fMRI activity signals across the brain. Our experiments demonstrate that NeuroBOLT effectively reconstructs unseen resting-state fMRI signals from primary sensory, high-level cognitive areas, and deep subcortical brain regions, achieving state-of-the-art accuracy with the potential to generalize across varying conditions and sites, which significantly advances the integration of these two modalities.

  • 10 authors
·
Oct 6, 2024

Decoding speech from non-invasive brain recordings

Decoding language from brain activity is a long-awaited goal in both healthcare and neuroscience. Major milestones have recently been reached thanks to intracranial devices: subject-specific pipelines trained on invasive brain responses to basic language tasks now start to efficiently decode interpretable features (e.g. letters, words, spectrograms). However, scaling this approach to natural speech and non-invasive brain recordings remains a major challenge. Here, we propose a single end-to-end architecture trained with contrastive learning across a large cohort of individuals to predict self-supervised representations of natural speech. We evaluate our model on four public datasets, encompassing 169 volunteers recorded with magneto- or electro-encephalography (M/EEG), while they listened to natural speech. The results show that our model can identify, from 3s of MEG signals, the corresponding speech segment with up to 72.5% top-10 accuracy out of 1,594 distinct segments (and 44% top-1 accuracy), and up to 19.1% out of 2,604 segments for EEG recordings -- hence allowing the decoding of phrases absent from the training set. Model comparison and ablation analyses show that these performances directly benefit from our original design choices, namely the use of (i) a contrastive objective, (ii) pretrained representations of speech and (iii) a common convolutional architecture simultaneously trained across several participants. Together, these results delineate a promising path to decode natural language processing in real time from non-invasive recordings of brain activity.

  • 5 authors
·
Aug 25, 2022 1

Comparison Against Task Driven Artificial Neural Networks Reveals Functional Organization of Mouse Visual Cortex

Partially inspired by features of computation in visual cortex, deep neural networks compute hierarchical representations of their inputs. While these networks have been highly successful in machine learning, it remains unclear to what extent they can aid our understanding of cortical function. Several groups have developed metrics that provide a quantitative comparison between representations computed by networks and representations measured in cortex. At the same time, neuroscience is well into an unprecedented phase of large-scale data collection, as evidenced by projects such as the Allen Brain Observatory. Despite the magnitude of these efforts, in a given experiment only a fraction of units are recorded, limiting the information available about the cortical representation. Moreover, only a finite number of stimuli can be shown to an animal over the course of a realistic experiment. These limitations raise the question of how and whether metrics that compare representations of deep networks are meaningful on these datasets. Here, we empirically quantify the capabilities and limitations of these metrics due to limited image presentations and neuron samples. We find that the comparison procedure is robust to different choices of stimuli set and the level of subsampling that one might expect in a large-scale brain survey with thousands of neurons. Using these results, we compare the representations measured in the Allen Brain Observatory in response to natural image presentations to deep neural network. We show that the visual cortical areas are relatively high order representations (in that they map to deeper layers of convolutional neural networks). Furthermore, we see evidence of a broad, more parallel organization rather than a sequential hierarchy, with the primary area VISp(V1) being lower order relative to the other areas.

  • 3 authors
·
Nov 18, 2019

BrainSCUBA: Fine-Grained Natural Language Captions of Visual Cortex Selectivity

Understanding the functional organization of higher visual cortex is a central focus in neuroscience. Past studies have primarily mapped the visual and semantic selectivity of neural populations using hand-selected stimuli, which may potentially bias results towards pre-existing hypotheses of visual cortex functionality. Moving beyond conventional approaches, we introduce a data-driven method that generates natural language descriptions for images predicted to maximally activate individual voxels of interest. Our method -- Semantic Captioning Using Brain Alignments ("BrainSCUBA") -- builds upon the rich embedding space learned by a contrastive vision-language model and utilizes a pre-trained large language model to generate interpretable captions. We validate our method through fine-grained voxel-level captioning across higher-order visual regions. We further perform text-conditioned image synthesis with the captions, and show that our images are semantically coherent and yield high predicted activations. Finally, to demonstrate how our method enables scientific discovery, we perform exploratory investigations on the distribution of "person" representations in the brain, and discover fine-grained semantic selectivity in body-selective areas. Unlike earlier studies that decode text, our method derives voxel-wise captions of semantic selectivity. Our results show that BrainSCUBA is a promising means for understanding functional preferences in the brain, and provides motivation for further hypothesis-driven investigation of visual cortex.

  • 4 authors
·
Oct 6, 2023

Zero-Shot Imagined Speech Decoding via Imagined-to-Listened MEG Mapping

Decoding imagined speech from non-invasive brain recordings is challenging because imagined datasets are scarce and difficult to align temporally across subjects and sessions In this work, we propose a new approach to the decoding of imagined speech that leverages the richer and more reliably labeled recordings during listening to speech. We collected paired listened and imagined MEG recordings to rhythmic melodic and spoken stimuli from trained musicians. Using trained musicians helped improve temporal alignment across conditions. We then developed a three-stage decoding pipeline that revealed consistent and meaningful relationships between neural activity evoked by imagining and listening to the same stimuli. First, we trained six linear and neural models to map imagined MEG responses to listened responses. We evaluated these models against a null baseline from unseen subjects to validate that the predicted-listening responses preserve stimulus-specific information. In the second stage, we trained a contrastive word decoder exclusively on the listened MEG responses, and evaluated it using four embedding strategies including semantic, acoustic, and phonetic representations. In the third stage, we process the imagined MEG responses from held-out subjects through the mapping pipeline to compute the corresponding listening responses that are then decoded by the listened decoder. Using rank-based analysis, we show that the imagined words are decodable significantly above chance. We shall report here the results of a proof-of-concept implementation to decode imagined speech, where all evaluations are performed on held-out subjects. We also demonstrate that performance improves with training data size, suggesting that this approach is scalable and can directly be made applicable to realistic brain-computer interface scenarios.

  • 2 authors
·
May 7 1

AAD-LLM: Neural Attention-Driven Auditory Scene Understanding

Auditory foundation models, including auditory large language models (LLMs), process all sound inputs equally, independent of listener perception. However, human auditory perception is inherently selective: listeners focus on specific speakers while ignoring others in complex auditory scenes. Existing models do not incorporate this selectivity, limiting their ability to generate perception-aligned responses. To address this, we introduce Intention-Informed Auditory Scene Understanding (II-ASU) and present Auditory Attention-Driven LLM (AAD-LLM), a prototype system that integrates brain signals to infer listener attention. AAD-LLM extends an auditory LLM by incorporating intracranial electroencephalography (iEEG) recordings to decode which speaker a listener is attending to and refine responses accordingly. The model first predicts the attended speaker from neural activity, then conditions response generation on this inferred attentional state. We evaluate AAD-LLM on speaker description, speech transcription and extraction, and question answering in multitalker scenarios, with both objective and subjective ratings showing improved alignment with listener intention. By taking a first step toward intention-aware auditory AI, this work explores a new paradigm where listener perception informs machine listening, paving the way for future listener-centered auditory systems. Demo and code available: https://aad-llm.github.io.

  • 9 authors
·
Feb 23, 2025 3

Incorporating brain-inspired mechanisms for multimodal learning in artificial intelligence

Multimodal learning enhances the perceptual capabilities of cognitive systems by integrating information from different sensory modalities. However, existing multimodal fusion research typically assumes static integration, not fully incorporating key dynamic mechanisms found in the brain. Specifically, the brain exhibits an inverse effectiveness phenomenon, wherein weaker unimodal cues yield stronger multisensory integration benefits; conversely, when individual modal cues are stronger, the effect of fusion is diminished. This mechanism enables biological systems to achieve robust cognition even with scarce or noisy perceptual cues. Inspired by this biological mechanism, we explore the relationship between multimodal output and information from individual modalities, proposing an inverse effectiveness driven multimodal fusion (IEMF) strategy. By incorporating this strategy into neural networks, we achieve more efficient integration with improved model performance and computational efficiency, demonstrating up to 50% reduction in computational cost across diverse fusion methods. We conduct experiments on audio-visual classification, continual learning, and question answering tasks to validate our method. Results consistently demonstrate that our method performs excellently in these tasks. To verify universality and generalization, we also conduct experiments on Artificial Neural Networks (ANN) and Spiking Neural Networks (SNN), with results showing good adaptability to both network types. Our research emphasizes the potential of incorporating biologically inspired mechanisms into multimodal networks and provides promising directions for the future development of multimodal artificial intelligence. The code is available at https://github.com/Brain-Cog-Lab/IEMF.

  • 6 authors
·
May 15, 2025 2

In-the-wild Audio Spatialization with Flexible Text-guided Localization

To enhance immersive experiences, binaural audio offers spatial awareness of sounding objects in AR, VR, and embodied AI applications. While existing audio spatialization methods can generally map any available monaural audio to binaural audio signals, they often lack the flexible and interactive control needed in complex multi-object user-interactive environments. To address this, we propose a Text-guided Audio Spatialization (TAS) framework that utilizes flexible text prompts and evaluates our model from unified generation and comprehension perspectives. Due to the limited availability of premium and large-scale stereo data, we construct the SpatialTAS dataset, which encompasses 376,000 simulated binaural audio samples to facilitate the training of our model. Our model learns binaural differences guided by 3D spatial location and relative position prompts, augmented by flipped-channel audio. It outperforms existing methods on both simulated and real-recorded datasets, demonstrating superior generalization and accuracy. Besides, we develop an assessment model based on Llama-3.1-8B, which evaluates the spatial semantic coherence between our generated binaural audio and text prompts through a spatial reasoning task. Results demonstrate that text prompts provide flexible and interactive control to generate binaural audio with excellent quality and semantic consistency in spatial locations. Dataset is available at https://github.com/Alice01010101/TASU

  • 5 authors
·
Jun 1, 2025

Acoustic Prompt Tuning: Empowering Large Language Models with Audition Capabilities

The auditory system plays a substantial role in shaping the overall human perceptual experience. While prevailing large language models (LLMs) and visual language models (VLMs) have shown their promise in solving a wide variety of vision and language understanding tasks, only a few of them can be generalised to the audio domain without compromising their domain-specific capacity. In this work, we introduce Acoustic Prompt Turning (APT), a new adapter extending LLMs and VLMs to the audio domain by soft prompting only. Specifically, APT applies an instruction-aware audio aligner to generate soft prompts, conditioned on both input text and sounds, as language model inputs. To mitigate the data scarcity in the audio domain, a multi-task learning strategy is proposed by formulating diverse audio tasks in a sequence-to-sequence manner. Moreover, we improve the framework of audio language model by using interleaved audio-text embeddings as the input sequence. This improved framework imposes zero constraints on the input format and thus is capable of tackling more understanding tasks, such as few-shot audio classification and audio reasoning. To further evaluate the reasoning ability of audio networks, we propose natural language audio reasoning (NLAR), a new task that analyses across two audio clips by comparison and summarization. Experiments show that APT-enhanced LLMs (namely APT-LLMs) achieve competitive results compared to the expert models (i.e., the networks trained on the targeted datasets) across various tasks. We finally demonstrate the APT's ability in extending frozen VLMs to the audio domain without finetuning, achieving promising results in the audio-visual question and answering task. Our code and model weights are released at https://github.com/JinhuaLiang/APT.

  • 6 authors
·
Nov 30, 2023

Meta-Learning an In-Context Transformer Model of Human Higher Visual Cortex

Understanding functional representations within higher visual cortex is a fundamental question in computational neuroscience. While artificial neural networks pretrained on large-scale datasets exhibit striking representational alignment with human neural responses, learning image-computable models of visual cortex relies on individual-level, large-scale fMRI datasets. The necessity for expensive, time-intensive, and often impractical data acquisition limits the generalizability of encoders to new subjects and stimuli. BraInCoRL uses in-context learning to predict voxelwise neural responses from few-shot examples without any additional finetuning for novel subjects and stimuli. We leverage a transformer architecture that can flexibly condition on a variable number of in-context image stimuli, learning an inductive bias over multiple subjects. During training, we explicitly optimize the model for in-context learning. By jointly conditioning on image features and voxel activations, our model learns to directly generate better performing voxelwise models of higher visual cortex. We demonstrate that BraInCoRL consistently outperforms existing voxelwise encoder designs in a low-data regime when evaluated on entirely novel images, while also exhibiting strong test-time scaling behavior. The model also generalizes to an entirely new visual fMRI dataset, which uses different subjects and fMRI data acquisition parameters. Further, BraInCoRL facilitates better interpretability of neural signals in higher visual cortex by attending to semantically relevant stimuli. Finally, we show that our framework enables interpretable mappings from natural language queries to voxel selectivity.

  • 9 authors
·
May 21, 2025 2

Brain3D: Generating 3D Objects from fMRI

Understanding the hidden mechanisms behind human's visual perception is a fundamental question in neuroscience. To that end, investigating into the neural responses of human mind activities, such as functional Magnetic Resonance Imaging (fMRI), has been a significant research vehicle. However, analyzing fMRI signals is challenging, costly, daunting, and demanding for professional training. Despite remarkable progress in fMRI analysis, existing approaches are limited to generating 2D images and far away from being biologically meaningful and practically useful. Under this insight, we propose to generate visually plausible and functionally more comprehensive 3D outputs decoded from brain signals, enabling more sophisticated modeling of fMRI data. Conceptually, we reformulate this task as a {\em fMRI conditioned 3D object generation} problem. We design a novel 3D object representation learning method, Brain3D, that takes as input the fMRI data of a subject who was presented with a 2D image, and yields as output the corresponding 3D object images. The key capabilities of this model include tackling the noises with high-level semantic signals and a two-stage architecture design for progressive high-level information integration. Extensive experiments validate the superior capability of our model over previous state-of-the-art 3D object generation methods. Importantly, we show that our model captures the distinct functionalities of each region of human vision system as well as their intricate interplay relationships, aligning remarkably with the established discoveries in neuroscience. Further, preliminary evaluations indicate that Brain3D can successfully identify the disordered brain regions in simulated scenarios, such as V1, V2, V3, V4, and the medial temporal lobe (MTL) within the human visual system. Our data and code will be available at https://brain-3d.github.io/.

  • 7 authors
·
May 24, 2024

Cross-Species RSA Reveals Conserved Early Visual Alignment but Divergent Higher-Area Rankings Across Human fMRI and Macaque Electrophysiology

Does the relationship between learning rules and brain alignment generalize across species? We extend our prior finding that untrained CNNs match backpropagation at human V1 by testing the same five learning rules against macaque electrophysiology. The rules are backpropagation (BP), feedback alignment (FA), predictive coding (PC), spike-timing-dependent plasticity (STDP), and an untrained random-weights baseline. The macaque data come from two datasets: MajajHong2015 (V4/IT, 3,200 stimulus presentations, 88/168 neurons) and FreemanZiemba2013 (V1/V2, 135 stimuli, 102/103 neurons). Using RSA with identical model weights from our human study, we find: (1) all models achieve higher alignment with macaque early visual cortex (rho = 0.15-0.30 at V1/V2) than with human fMRI (rho = 0.01-0.08), consistent with the higher signal-to-noise ratio of electrophysiology; (2) STDP and PC produce the highest macaque V1/V2 alignment (rho ~ 0.30 and 0.28), consistent with their leading position among trained rules in human V1; (3) at IT, learning rule rankings show no detectable correlation across species (Kendall's tau = 0.00, p = 1.00), though this null result is expected given that n = 5 provides power only at tau = +/-1.0, and is further confounded by stimulus set differences; (4) a pretrained ResNet-50 (ImageNet) achieves rho = 0.25 at macaque IT, substantially above all custom CNN conditions (rho = 0.07-0.14), suggesting IT alignment is limited by model capacity and training data rather than by the learning rule. Noise ceilings, multi-seed variability (5 seeds), and a stimulus-control analysis are reported. These results demonstrate that early visual alignment is robust across species, while higher-area alignment is modulated by model capacity and stimulus domain.

  • 1 authors
·
May 20

Hierarchical Frequency Tagging Probe (HFTP): A Unified Approach to Investigate Syntactic Structure Representations in Large Language Models and the Human Brain

Large Language Models (LLMs) demonstrate human-level or even superior language abilities, effectively modeling syntactic structures, yet the specific computational modules responsible remain unclear. A key question is whether LLM behavioral capabilities stem from mechanisms akin to those in the human brain. To address these questions, we introduce the Hierarchical Frequency Tagging Probe (HFTP), a tool that utilizes frequency-domain analysis to identify neuron-wise components of LLMs (e.g., individual Multilayer Perceptron (MLP) neurons) and cortical regions (via intracranial recordings) encoding syntactic structures. Our results show that models such as GPT-2, Gemma, Gemma 2, Llama 2, Llama 3.1, and GLM-4 process syntax in analogous layers, while the human brain relies on distinct cortical regions for different syntactic levels. Representational similarity analysis reveals a stronger alignment between LLM representations and the left hemisphere of the brain (dominant in language processing). Notably, upgraded models exhibit divergent trends: Gemma 2 shows greater brain similarity than Gemma, while Llama 3.1 shows less alignment with the brain compared to Llama 2. These findings offer new insights into the interpretability of LLM behavioral improvements, raising questions about whether these advancements are driven by human-like or non-human-like mechanisms, and establish HFTP as a valuable tool bridging computational linguistics and cognitive neuroscience. This project is available at https://github.com/LilTiger/HFTP.

  • 10 authors
·
Oct 15, 2025 2

MACS: Multi-source Audio-to-image Generation with Contextual Significance and Semantic Alignment

Propelled by the breakthrough in deep generative models, audio-to-image generation has emerged as a pivotal cross-model task that converts complex auditory signals into rich visual representations. However, previous works only focus on single-source audio inputs for image generation, ignoring the multi-source characteristic in natural auditory scenes, thus limiting the performance in generating comprehensive visual content. To bridge this gap, a method called MACS is proposed to conduct multi-source audio-to-image generation. This is the first work that explicitly separates multi-source audio to capture the rich audio components before image generation. MACS is a two-stage method. In the first stage, multi-source audio inputs are separated by a weakly supervised method, where the audio and text labels are semantically aligned by casting into a common space using the large pre-trained CLAP model. We introduce a ranking loss to consider the contextual significance of the separated audio signals. In the second stage, efficient image generation is achieved by mapping the separated audio signals to the generation condition using only a trainable adapter and a MLP layer. We preprocess the LLP dataset as the first full multi-source audio-to-image generation benchmark. The experiments are conducted on multi-source, mixed-source, and single-source audio-to-image generation tasks. The proposed MACS outperforms the current state-of-the-art methods in 17 of the 21 evaluation indexes on all tasks and delivers superior visual quality. The code will be publicly available.

  • 4 authors
·
Mar 13, 2025

NeuroSonic: Conditional Flow Matching for EEG-to-Speech Reconstruction

Reconstructing continuous speech from scalp electroencephalography (EEG) remains fundamentally challenging. EEG provides a weak, spatially diffuse, and highly variable measurement of distributed cortical activity, whereas speech is organized as a coherent acoustic trajectory with strong harmonic and temporal structure. The resulting mismatch makes waveform regression unstable and causes stochastic multi-step generation to be sensitive to artifact-dependent conditioning and subject variability. We introduce NeuroSonic, a conditional flow-matching framework for EEG-to-speech reconstruction. Instead of predicting waveforms directly or refining them through stochastic denoising, NeuroSonic learns a deterministic probability-flow velocity field that transports a noise-corrupted acoustic state toward clean speech under EEG conditioning. EEG and audio are embedded into a shared token space and processed by a time-conditioned gated Transformer that parameterizes the transport ordinary differential equation. This formulation models trajectory evolution explicitly while avoiding iterative stochastic sampling. We evaluate NeuroSonic on the CineBrain and EAV benchmarks under cross-subject evaluation. Across both datasets, the proposed method improves distributional realism, spectral fidelity, and perceptual quality over representative GAN-, diffusion-, and mean-flow baselines, with up to a 26.3\% gain in overall perceptual quality. The performance gap is most evident in artifact-heavy segments, where conditioning variability is strongest. These findings indicate that deterministic conditional transport provides a stable and effective formulation for EEG-driven speech reconstruction. Code is available at https://github.com/Y-Research-SBU/NeuroSonic/ .

  • 6 authors
·
Jun 22

The Differentiable Auditory Loop (DAL): An ML Framework for Hyper-Personalized Hearing Aids

Conventional hearing aids rely on fixed, frequency-dependent amplification and compression to manage reduced sensitivity, which often fails to provide sufficient listening support in complex environments, such as situations with multiple speakers (the ``cocktail party'' problem). To more comprehensively address the underlying encoding dysfunctions of hearing loss, we introduce the Differentiable Auditory Loop (DAL), a new open-source framework for personalized hearing aid design and fitting. Our first implementation of DAL incorporates CARFAC, a differentiable model of human cochlear function, which we ported to JAX, to optimize a deep neural network to match impaired auditory neural activity patterns with a normal-hearing reference. To build a hearing aid with the fine-grained spectro-temporal signal processing required, we adopt SEANet, a waveform-to-waveform fully convolutional UNet generator. We fine-tune the network by comparing the outputs of a CARFAC model fitted to normal hearing with that of a CARFAC model fitted to match each subject's individual hearing impairment. The comparison is done using loss functions derived from the respective CARFAC neural activity pattern (NAP) outputs and stabilized auditory images (SAIs), the latter providing a 2D representation that captures phase-insensitive temporal structure in the auditory nerve output. Through gradient descent, the SEANet model learns to both denoise the input and compensate for the hearing loss modelled by the impaired CARFAC model. Across neural-representation and signal-fidelity metrics, the DAL-optimized SEANet model outperformed the tested master hearing aid (MHA) baselines. The DAL framework provides a practical path toward model-based, machine-learning-driven personalization of hearing aid signal processing. Next steps include hardware deployment to enable real-world clinical testing.

  • 6 authors
·
Jun 1

Brain Diffusion for Visual Exploration: Cortical Discovery using Large Scale Generative Models

A long standing goal in neuroscience has been to elucidate the functional organization of the brain. Within higher visual cortex, functional accounts have remained relatively coarse, focusing on regions of interest (ROIs) and taking the form of selectivity for broad categories such as faces, places, bodies, food, or words. Because the identification of such ROIs has typically relied on manually assembled stimulus sets consisting of isolated objects in non-ecological contexts, exploring functional organization without robust a priori hypotheses has been challenging. To overcome these limitations, we introduce a data-driven approach in which we synthesize images predicted to activate a given brain region using paired natural images and fMRI recordings, bypassing the need for category-specific stimuli. Our approach -- Brain Diffusion for Visual Exploration ("BrainDiVE") -- builds on recent generative methods by combining large-scale diffusion models with brain-guided image synthesis. Validating our method, we demonstrate the ability to synthesize preferred images with appropriate semantic specificity for well-characterized category-selective ROIs. We then show that BrainDiVE can characterize differences between ROIs selective for the same high-level category. Finally we identify novel functional subdivisions within these ROIs, validated with behavioral data. These results advance our understanding of the fine-grained functional organization of human visual cortex, and provide well-specified constraints for further examination of cortical organization using hypothesis-driven methods.

  • 4 authors
·
Jun 5, 2023

Instruction-Tuned Video-Audio Models Elucidate Functional Specialization in the Brain

Recent voxel-wise multimodal brain encoding studies have shown that multimodal large language models (MLLMs) exhibit a higher degree of brain alignment compared to unimodal models in both unimodal and multimodal stimulus settings. More recently, instruction-tuned multimodal models have shown to generate task-specific representations that align strongly with brain activity. However, prior work evaluating the brain alignment of MLLMs has primarily focused on unimodal settings or relied on non-instruction-tuned multimodal models for multimodal stimuli. To address this gap, we investigated brain alignment, that is, measuring the degree of predictivity of neural activity recorded while participants were watching naturalistic movies (video along with audio) with representations derived from MLLMs. We utilized instruction-specific embeddings from six video and two audio instruction-tuned MLLMs. Experiments with 13 video task-specific instructions show that instruction-tuned video MLLMs significantly outperform non-instruction-tuned multimodal (by 15%) and unimodal models (by 20%). Our evaluation of MLLMs for both video and audio tasks using language-guided instructions shows clear disentanglement in task-specific representations from MLLMs, leading to precise differentiation of multimodal functional processing in the brain. We also find that MLLM layers align hierarchically with the brain, with early sensory areas showing strong alignment with early layers, while higher-level visual and language regions align more with middle to late layers. These findings provide clear evidence for the role of task-specific instructions in improving the alignment between brain activity and MLLMs, and open new avenues for mapping joint information processing in both the systems. We make the code publicly available [https://github.com/subbareddy248/mllm_videos].

  • 8 authors
·
Jun 9, 2025

PASE: Leveraging the Phonological Prior of WavLM for Low-Hallucination Generative Speech Enhancement

Generative models have shown remarkable performance in speech enhancement (SE), achieving superior perceptual quality over traditional discriminative approaches. However, existing generative SE approaches often overlook the risk of hallucination under severe noise, leading to incorrect spoken content or inconsistent speaker characteristics, which we term linguistic and acoustic hallucinations, respectively. We argue that linguistic hallucination stems from models' failure to constrain valid phonological structures and it is a more fundamental challenge. While language models (LMs) are well-suited for capturing the underlying speech structure through modeling the distribution of discrete tokens, existing approaches are limited in learning from noise-corrupted representations, which can lead to contaminated priors and hallucinations. To overcome these limitations, we propose the Phonologically Anchored Speech Enhancer (PASE), a generative SE framework that leverages the robust phonological prior embedded in the pre-trained WavLM model to mitigate hallucinations. First, we adapt WavLM into a denoising expert via representation distillation to clean its final-layer features. Guided by the model's intrinsic phonological prior, this process enables robust denoising while minimizing linguistic hallucinations. To further reduce acoustic hallucinations, we train the vocoder with a dual-stream representation: the high-level phonetic representation provides clean linguistic content, while a low-level acoustic representation retains speaker identity and prosody. Experimental results demonstrate that PASE not only surpasses state-of-the-art discriminative models in perceptual quality, but also significantly outperforms prior generative models with substantially lower linguistic and acoustic hallucinations.

  • 5 authors
·
Nov 17, 2025

Listen, Think, and Understand

The ability of artificial intelligence (AI) systems to perceive and comprehend audio signals is crucial for many applications. Although significant progress has been made in this area since the development of AudioSet, most existing models are designed to map audio inputs to pre-defined, discrete sound label sets. In contrast, humans possess the ability to not only classify sounds into coarse-grained categories, but also to listen to the details of the sounds, explain the reason for the predictions, think what the sound infers, and understand the scene and what action needs to be taken. Such capabilities beyond perception are not yet present in existing audio models. On the other hand, modern large language models (LLMs) exhibit emerging reasoning ability but they lack audio perception capabilities. Therefore, we ask the question: can we build an AI model that has both audio perception and a reasoning ability? In this paper, we propose a novel audio foundation model, called LTU (Listen, Think, and Understand). To train LTU, we created a new OpenAQA-5M dataset consisting of 1.9 million closed-ended and 3.7 million open-ended, diverse (audio, question, answer) tuples, and used an autoregressive training framework and a perception-to-understanding curriculum. LTU demonstrates strong performance and generalization ability on conventional audio tasks such as classification and captioning. Moreover, it exhibits remarkable reasoning and comprehension abilities in the audio domain. To the best of our knowledge, LTU is the first audio-enabled large language model that bridges audio perception with advanced reasoning.

  • 5 authors
·
May 18, 2023

Hallucinations in Neural Automatic Speech Recognition: Identifying Errors and Hallucinatory Models

Hallucinations are a type of output error produced by deep neural networks. While this has been studied in natural language processing, they have not been researched previously in automatic speech recognition. Here, we define hallucinations in ASR as transcriptions generated by a model that are semantically unrelated to the source utterance, yet still fluent and coherent. The similarity of hallucinations to probable natural language outputs of the model creates a danger of deception and impacts the credibility of the system. We show that commonly used metrics, such as word error rates, cannot differentiate between hallucinatory and non-hallucinatory models. To address this, we propose a perturbation-based method for assessing the susceptibility of an automatic speech recognition (ASR) model to hallucination at test time, which does not require access to the training dataset. We demonstrate that this method helps to distinguish between hallucinatory and non-hallucinatory models that have similar baseline word error rates. We further explore the relationship between the types of ASR errors and the types of dataset noise to determine what types of noise are most likely to create hallucinatory outputs. We devise a framework for identifying hallucinations by analysing their semantic connection with the ground truth and their fluency. Finally, we discover how to induce hallucinations with a random noise injection to the utterance.

  • 2 authors
·
Jan 3, 2024

Du-IN: Discrete units-guided mask modeling for decoding speech from Intracranial Neural signals

Invasive brain-computer interfaces have garnered significant attention due to their high performance. The current intracranial stereoElectroEncephaloGraphy (sEEG) foundation models typically build univariate representations based on a single channel. Some of them further use Transformer to model the relationship among channels. However, due to the locality and specificity of brain computation, their performance on more difficult tasks, e.g., speech decoding, which demands intricate processing in specific brain regions, is yet to be fully investigated. We hypothesize that building multi-variate representations within certain brain regions can better capture the specific neural processing. To explore this hypothesis, we collect a well-annotated Chinese word-reading sEEG dataset, targeting language-related brain networks, over 12 subjects. Leveraging this benchmark dataset, we developed the Du-IN model that can extract contextual embeddings from specific brain regions through discrete codebook-guided mask modeling. Our model achieves SOTA performance on the downstream 61-word classification task, surpassing all baseline models. Model comparison and ablation analysis reveal that our design choices, including (i) multi-variate representation by fusing channels in vSMC and STG regions and (ii) self-supervision by discrete codebook-guided mask modeling, significantly contribute to these performances. Collectively, our approach, inspired by neuroscience findings, capitalizing on multi-variate neural representation from specific brain regions, is suitable for invasive brain modeling. It marks a promising neuro-inspired AI approach in BCI.

  • 9 authors
·
May 19, 2024

Look Once to Hear: Target Speech Hearing with Noisy Examples

In crowded settings, the human brain can focus on speech from a target speaker, given prior knowledge of how they sound. We introduce a novel intelligent hearable system that achieves this capability, enabling target speech hearing to ignore all interfering speech and noise, but the target speaker. A naive approach is to require a clean speech example to enroll the target speaker. This is however not well aligned with the hearable application domain since obtaining a clean example is challenging in real world scenarios, creating a unique user interface problem. We present the first enrollment interface where the wearer looks at the target speaker for a few seconds to capture a single, short, highly noisy, binaural example of the target speaker. This noisy example is used for enrollment and subsequent speech extraction in the presence of interfering speakers and noise. Our system achieves a signal quality improvement of 7.01 dB using less than 5 seconds of noisy enrollment audio and can process 8 ms of audio chunks in 6.24 ms on an embedded CPU. Our user studies demonstrate generalization to real-world static and mobile speakers in previously unseen indoor and outdoor multipath environments. Finally, our enrollment interface for noisy examples does not cause performance degradation compared to clean examples, while being convenient and user-friendly. Taking a step back, this paper takes an important step towards enhancing the human auditory perception with artificial intelligence. We provide code and data at: https://github.com/vb000/LookOnceToHear.

  • 5 authors
·
May 10, 2024

Step-Audio-R1.5 Technical Report

Recent advancements in large audio language models have extended Chain-of-Thought (CoT) reasoning into the auditory domain, enabling models to tackle increasingly complex acoustic and spoken tasks. To elicit and sustain these extended reasoning chains, the prevailing paradigm -- driven by the success of text-based reasoning models -- overwhelmingly relies on Reinforcement Learning with Verified Rewards (RLVR). However, as models are strictly optimized to distill rich, continuous auditory contexts into isolated, verifiable text labels, a fundamental question arises: are we fostering true audio intelligence, or merely reducing a continuous sensory medium into a discrete puzzle? We identify this as the "verifiable reward trap." While RLVR yields remarkable scores on standardized objective benchmarks, it systematically degrades the real-world conversational feel of audio models. By prioritizing isolated correctness over acoustic nuance, RLVR reduces dynamic interactions to mechanical "answering machines," severely compromising prosodic naturalness, emotional continuity, and user immersion, particularly in long-turn dialogues. To bridge the gap between mechanical objective verification and genuine sensory empathy, we introduce Step-Audio-R1.5, marking a paradigm shift toward Reinforcement Learning from Human Feedback (RLHF) in audio reasoning. Comprehensive evaluations demonstrate that Step-Audio-R1.5 not only maintains robust analytical reasoning but profoundly transforms the interactive experience, redefining the boundaries of deeply immersive long-turn spoken dialogue.

stepfun-ai StepFun
·
Apr 27 2

PAL: Probing Audio Encoders via LLMs -- A Study of Information Transfer from Audio Encoders to LLMs

The integration of audio perception capabilities into Large Language Models (LLMs) has enabled significant advances in Audio-LLMs. Although application-focused developments, particularly in curating training data for specific capabilities e.g., audio reasoning, have progressed rapidly, the underlying mechanisms that govern efficient transfer of rich semantic representations from audio encoders to LLMs remain under-explored. We conceptualize effective audio-LLM interaction as the LLM's ability to proficiently probe the audio encoder representations to satisfy textual queries. This paper presents a systematic investigation on how architectural design choices can affect that. Beginning with a standard Pengi/LLaVA-style audio-LLM architecture, we propose and evaluate several modifications guided by hypotheses derived from mechanistic interpretability studies and LLM operational principles. Our experiments demonstrate that: (1) delaying audio integration until the LLM's initial layers establish textual context that enhances its ability to probe the audio representations for relevant information; (2) the LLM can proficiently probe audio representations exclusively through LLM layer's attention submodule, without requiring propagation to its Feed-Forward Network (FFN) submodule; (3) an efficiently integrated ensemble of diverse audio encoders provides richer, complementary representations, thereby broadening the LLM's capacity to probe a wider spectrum of audio information. All hypotheses are evaluated using an identical three-stage training curriculum on a dataset of 5.6 million audio-text pairs, ensuring controlled comparisons. Our final architecture, which incorporates all proposed modifications, achieves relative improvements from 10\% to 60\% over the baseline, validating our approach to optimizing cross-modal information transfer in audio-LLMs. Project page: https://ta012.github.io/PAL/

  • 7 authors
·
Jun 12, 2025

RABBiT: Rapidly adaptive BOLD foundation model via brain-tuning for accurate zero-shot and few-shot prediction of speech-elicited responses in the brain

Language understanding in the brain is context-dependent, varying across experimental stimuli and individuals, which makes it difficult to build computational models that generalize across both. This calls for a foundation model of language-evoked brain activity that can capture shared structure while adapting efficiently to new participants and inputs. We introduce RABBiT (Rapidly Adaptive BOLD foundation model via BraIn-Tuning), a compact audio-to-fMRI encoder designed for accurate zero- and few-shot prediction. A comprehensive evaluation on 324 participants across multiple unseen fMRI datasets shows that RABBiT enables accurate zero-shot prediction of fMRI responses to natural speech across auditory and language-selective regions, surpassing the SOTA foundation model for fMRI and predictions based on group averages. With as little as 10 minutes of participant-specific data, RABBiT further improves performance via parameter-efficient tuning, substantially outperforming per-participant linear models. RABBiT's performance is driven by two key innovations: (1) learned region-specific attention, and (2) a decomposition of brain responses into shared and subject-specific components, combined with a brain-tuned speech backbone. In addition to supporting strong predictive accuracy, the structured, region-specific representations that RABBiT learns enable interpretability. By eliminating the need for extensive per-participant data and model fitting, RABBiT enables scalable population-level analyses of language in the human brain. We make the code available at https://github.com/bridge-ai-neuro/rabbit.

  • 2 authors
·
Jul 5

Scaling Law in Neural Data: Non-Invasive Speech Decoding with 175 Hours of EEG Data

Brain-computer interfaces (BCIs) hold great potential for aiding individuals with speech impairments. Utilizing electroencephalography (EEG) to decode speech is particularly promising due to its non-invasive nature. However, recordings are typically short, and the high variability in EEG data has led researchers to focus on classification tasks with a few dozen classes. To assess its practical applicability for speech neuroprostheses, we investigate the relationship between the size of EEG data and decoding accuracy in the open vocabulary setting. We collected extensive EEG data from a single participant (175 hours) and conducted zero-shot speech segment classification using self-supervised representation learning. The model trained on the entire dataset achieved a top-1 accuracy of 48\% and a top-10 accuracy of 76\%, while mitigating the effects of myopotential artifacts. Conversely, when the data was limited to the typical amount used in practice (sim10 hours), the top-1 accuracy dropped to 2.5\%, revealing a significant scaling effect. Additionally, as the amount of training data increased, the EEG latent representation progressively exhibited clearer temporal structures of spoken phrases. This indicates that the decoder can recognize speech segments in a data-driven manner without explicit measurements of word recognition. This research marks a significant step towards the practical realization of EEG-based speech BCIs.

  • 6 authors
·
Jul 9, 2024

Taste-aware music retrieval from audio embeddings

Crossmodal correspondences between sound and taste are well established in psychology and neuroscience, but largely absent from content-based multimedia retrieval. We formalise taste-from-audio prediction as a content-based music information retrieval benchmark over a perceptually validated multi-source corpus, comparing ten frozen audio encoders from the four HEAR families under a shared multi-task regression head, with gated late-fusion as a configurable variant. In order to assess the effectiveness of the models, we compute absolute error and rank correlation. The strongest systems predict the five tastes within a macro RMSE of 0.134; on held-out real music their error is less than half a single rater's deviation from the consensus (RMSE 0.13 vs. 0.28), so the model tracks the group consensus more closely than an average human rater, and well below the previous state of the art baseline (0.219). On absolute error the encoders are statistically flat, with a single VGGish matching the best fusion, but gated late-fusion's advantage is confined to rank correlation (macro Pearson r 0.724 vs. 0.666). Operationalised as a content-based retrieval index, the predicted taste space ranks a 309-item pool far more faithfully than a CLAP-text baseline, which sits at chance; ridge probes and an audio-bandstop knockout read the strongest representations against documented sound-taste correspondences.

CortexCompile: Harnessing Cortical-Inspired Architectures for Enhanced Multi-Agent NLP Code Synthesis

Current approaches to automated code generation often rely on monolithic models that lack real-time adaptability and scalability. This limitation is particularly evident in complex programming tasks that require dynamic adjustment and efficiency. The integration of neuroscience principles into Natural Language Processing (NLP) has the potential to revolutionize automated code generation. This paper presents CortexCompile, a novel modular system inspired by the specialized functions of the human brain's cortical regions. By emulating the distinct roles of the Prefrontal Cortex, Parietal Cortex, Temporal Lobe, and Motor Cortex, CortexCompile achieves significant advancements in scalability, efficiency, and adaptability compared to traditional monolithic models like GPT-4o. The system's architecture features a Task Orchestration Agent that manages dynamic task delegation and parallel processing, facilitating the generation of highly accurate and optimized code across increasingly complex programming tasks. Experimental evaluations demonstrate that CortexCompile consistently outperforms GPT-4o in development time, accuracy, and user satisfaction, particularly in tasks involving real-time strategy games and first-person shooters. These findings underscore the viability of neuroscience-inspired architectures in addressing the limitations of current NLP models, paving the way for more efficient and human-like AI systems.

  • 2 authors
·
Aug 23, 2024

OmniDPO: A Preference Optimization Framework to Address Omni-Modal Hallucination

Recently, Omni-modal large language models (OLLMs) have sparked a new wave of research, achieving impressive results in tasks such as audio-video understanding and real-time environment perception. However, hallucination issues still persist. Similar to the bimodal setting, the priors from the text modality tend to dominate, leading OLLMs to rely more heavily on textual cues while neglecting visual and audio information. In addition, fully multimodal scenarios introduce new challenges. Most existing models align visual or auditory modalities with text independently during training, while ignoring the intrinsic correlations between video and its corresponding audio. This oversight results in hallucinations when reasoning requires interpreting hidden audio cues embedded in video content. To address these challenges, we propose OmniDPO, a preference-alignment framework designed to mitigate hallucinations in OLLMs. Specifically, OmniDPO incorporates two strategies: (1) constructing text-preference sample pairs to enhance the model's understanding of audio-video interactions; and (2) constructing multimodal-preference sample pairs to strengthen the model's attention to visual and auditory information. By tackling both challenges, OmniDPO effectively improves multimodal grounding and reduces hallucination. Experiments conducted on two OLLMs demonstrate that OmniDPO not only effectively mitigates multimodal hallucinations but also significantly enhances the models' reasoning capabilities across modalities. All code and datasets will be released upon paper acceptance.

  • 9 authors
·
Aug 31, 2025

Hallucination Detox: Sensitive Neuron Dropout (SeND) for Large Language Model Training

As large language models (LLMs) become increasingly deployed across various industries, concerns regarding their reliability, particularly due to hallucinations-outputs that are factually inaccurate or irrelevant to user input-have grown. Our research investigates the relationship between the training process and the emergence of hallucinations to address a key gap in existing research that focuses primarily on post hoc detection and mitigation strategies. Using models from the Pythia suite (70M-12B parameters) and several hallucination detection metrics, we analyze hallucination trends throughout training and explore LLM internal dynamics. We introduce SEnsitive Neuron Dropout (SeND), a novel training protocol designed to mitigate hallucinations by reducing variance during training. SeND achieves this by deterministically dropping neurons with significant variability on a dataset, referred to as Sensitive Neurons. In addition, we develop an unsupervised hallucination detection metric, Efficient EigenScore (EES), which approximates the traditional EigenScore in 2x speed. This efficient metric is integrated into our protocol, allowing SeND to be both computationally scalable and effective at reducing hallucinations. Our empirical evaluation demonstrates that our approach improves LLM reliability at test time by up to 40% compared to normal training while also providing an efficient method to improve factual accuracy when adapting LLMs to domains such as Wikipedia and Medical datasets.

  • 5 authors
·
Oct 20, 2024 2

Canonical Cortical Field Theories

We characterise the dynamics of neuronal activity, in terms of field theory, using neural units placed on a 2D-lattice modelling the cortical surface. The electrical activity of neuronal units was analysed with the aim of deriving a neural field model with a simple functional form that still able to predict or reproduce empirical findings. Each neural unit was modelled using a neural mass and the accompanying field theory was derived in the continuum limit. The field theory comprised coupled (real) Klein-Gordon fields, where predictions of the model fall within the range of experimental findings. These predictions included the frequency spectrum of electric activity measured from the cortex, which was derived using an equipartition of energy over eigenfunctions of the neural fields. Moreover, the neural field model was invariant, within a set of parameters, to the dynamical system used to model each neuronal mass. Specifically, topologically equivalent dynamical systems resulted in the same neural field model when connected in a lattice; indicating that the fields derived could be read as a canonical cortical field theory. We specifically investigated non-dispersive fields that provide a structure for the coding (or representation) of afferent information. Further elaboration of the ensuing neural field theory, including the effect of dispersive forces, could be of importance in the understanding of the cortical processing of information.

  • 3 authors
·
Aug 20, 2023

Decoding Visual Experience and Mapping Semantics through Whole-Brain Analysis Using fMRI Foundation Models

Neural decoding, the process of understanding how brain activity corresponds to different stimuli, has been a primary objective in cognitive sciences. Over the past three decades, advancements in functional Magnetic Resonance Imaging and machine learning have greatly improved our ability to map visual stimuli to brain activity, especially in the visual cortex. Concurrently, research has expanded into decoding more complex processes like language and memory across the whole brain, utilizing techniques to handle greater variability and improve signal accuracy. We argue that "seeing" involves more than just mapping visual stimuli onto the visual cortex; it engages the entire brain, as various emotions and cognitive states can emerge from observing different scenes. In this paper, we develop algorithms to enhance our understanding of visual processes by incorporating whole-brain activation maps while individuals are exposed to visual stimuli. We utilize large-scale fMRI encoders and Image generative models pre-trained on large public datasets, which are then fine-tuned through Image-fMRI contrastive learning. Our models hence can decode visual experience across the entire cerebral cortex, surpassing the traditional confines of the visual cortex. We first compare our method with state-of-the-art approaches to decoding visual processing and show improved predictive semantic accuracy by 43%. A network ablation analysis suggests that beyond the visual cortex, the default mode network contributes most to decoding stimuli, in line with the proposed role of this network in sense-making and semantic processing. Additionally, we implemented zero-shot imagination decoding on an extra validation dataset, achieving a p-value of 0.0206 for mapping the reconstructed images and ground-truth text stimuli, which substantiates the model's capability to capture semantic meanings across various scenarios.

  • 9 authors
·
Nov 11, 2024

Brain Harmony: A Multimodal Foundation Model Unifying Morphology and Function into 1D Tokens

We present Brain Harmony (BrainHarmonix), the first multimodal brain foundation model that unifies structural morphology and functional dynamics into compact 1D token representations. The model was pretrained on two of the largest neuroimaging datasets to date, encompassing 64,594 T1-weighted structural MRI 3D volumes (~ 14 million images) and 70,933 functional MRI (fMRI) time series. BrainHarmonix is grounded in two foundational neuroscience principles: structure complements function - structural and functional modalities offer distinct yet synergistic insights into brain organization; function follows structure - brain functional dynamics are shaped by cortical morphology. The modular pretraining process involves single-modality training with geometric pre-alignment followed by modality fusion through shared brain hub tokens. Notably, our dynamics encoder uniquely handles fMRI time series with heterogeneous repetition times (TRs), addressing a major limitation in existing models. BrainHarmonix is also the first to deeply compress high-dimensional neuroimaging signals into unified, continuous 1D tokens, forming a compact latent space of the human brain. BrainHarmonix achieves strong generalization across diverse downstream tasks, including neurodevelopmental and neurodegenerative disorder classification and cognition prediction - consistently outperforming previous approaches. Our models - pretrained on 8 H100 GPUs - aim to catalyze a new era of AI-driven neuroscience powered by large-scale multimodal neuroimaging.

  • 12 authors
·
Sep 29, 2025

A Survey of Large Audio Language Models: Generalization, Trustworthiness, and Outlook

The foundational capabilities established by Large Language Models (LLMs) have paved the way for Multimodal Large Language Models (MLLMs), within which Large Audio Language Models (LALMs) are essential for realizing universal auditory intelligence. Despite their remarkable performance, the escalation of LALMs' capabilities has significantly outpaced the development of systemic frameworks to ensure their trustworthiness. This survey provides a comprehensive investigation into the endogenous mechanisms of LALMs, detailing the architectural innovations and alignment algorithms that facilitate emergent reasoning. Specifically, we analyze how the transition to unified end-to-end frameworks and the integration of continuous acoustic signals inherently expand the attack surface. To rigorously evaluate the risks within these paradigms, we establish a comprehensive taxonomy of trustworthiness, categorizing critical vulnerabilities such as cross-modal jailbreaking, latent acoustic backdoors, and biometric privacy leakage. We review the state-of-the-art through six analytical pillars: hallucination, robustness, safety, privacy, fairness, and authentication. The profound imbalance between a mature offensive landscape and underdeveloped defenses further validates the critical trustworthiness gaps and multidimensional risks facing audio-centric intelligence. Finally, we propose a strategic roadmap advocating for "Defense-in-Depth" architectures, causal auditory world modeling, and intrinsic representation engineering to bridge the gap between empirical performance and intrinsically trustworthy audio intelligence. Our project has been uploaded to GitHub https://github.com/Kwwwww74/Awesome-Trustworthy-AudioLLMs.

Exploring Quality and Generalizability in Parameterized Neural Audio Effects

Deep neural networks have shown promise for music audio signal processing applications, often surpassing prior approaches, particularly as end-to-end models in the waveform domain. Yet results to date have tended to be constrained by low sample rates, noise, narrow domains of signal types, and/or lack of parameterized controls (i.e. "knobs"), making their suitability for professional audio engineering workflows still lacking. This work expands on prior research published on modeling nonlinear time-dependent signal processing effects associated with music production by means of a deep neural network, one which includes the ability to emulate the parameterized settings you would see on an analog piece of equipment, with the goal of eventually producing commercially viable, high quality audio, i.e. 44.1 kHz sampling rate at 16-bit resolution. The results in this paper highlight progress in modeling these effects through architecture and optimization changes, towards increasing computational efficiency, lowering signal-to-noise ratio, and extending to a larger variety of nonlinear audio effects. Toward these ends, the strategies employed involved a three-pronged approach: model speed, model accuracy, and model generalizability. Most of the presented methods provide marginal or no increase in output accuracy over the original model, with the exception of dataset manipulation. We found that limiting the audio content of the dataset, for example using datasets of just a single instrument, provided a significant improvement in model accuracy over models trained on more general datasets.

  • 2 authors
·
Jun 9, 2020

DeSTA2.5-Audio: Toward General-Purpose Large Audio Language Model with Self-Generated Cross-Modal Alignment

We introduce DeSTA2.5-Audio, a general-purpose Large Audio Language Model (LALM) designed for robust auditory perception and instruction-following, without requiring task-specific audio instruction-tuning. Recent LALMs typically augment Large Language Models (LLMs) with auditory capabilities by training on large-scale, manually curated or LLM-synthesized audio-instruction datasets. However, these approaches have often suffered from the catastrophic forgetting of the LLM's original language abilities. To address this, we revisit the data construction pipeline and propose DeSTA, a self-generated cross-modal alignment strategy in which the backbone LLM generates its own training targets. This approach preserves the LLM's native language proficiency while establishing effective audio-text alignment, thereby enabling zero-shot generalization without task-specific tuning. Using DeSTA, we construct DeSTA-AQA5M, a large-scale, task-agnostic dataset containing 5 million training samples derived from 7,000 hours of audio spanning 50 diverse datasets, including speech, environmental sounds, and music. DeSTA2.5-Audio achieves state-of-the-art or competitive performance across a wide range of audio-language benchmarks, including Dynamic-SUPERB, MMAU, SAKURA, Speech-IFEval, and VoiceBench. Comprehensive comparative studies demonstrate that our self-generated strategy outperforms widely adopted data construction and training strategies in both auditory perception and instruction-following capabilities. Our findings underscore the importance of carefully designed data construction in LALM development and offer practical insights for building robust, general-purpose LALMs.

  • 28 authors
·
Jul 3, 2025

ChineseEEG-2: An EEG Dataset for Multimodal Semantic Alignment and Neural Decoding during Reading and Listening

EEG-based neural decoding requires large-scale benchmark datasets. Paired brain-language data across speaking, listening, and reading modalities are essential for aligning neural activity with the semantic representation of large language models (LLMs). However, such datasets are rare, especially for non-English languages. Here, we present ChineseEEG-2, a high-density EEG dataset designed for benchmarking neural decoding models under real-world language tasks. Building on our previous ChineseEEG dataset, which focused on silent reading, ChineseEEG-2 adds two active modalities: Reading Aloud (RA) and Passive Listening (PL), using the same Chinese corpus. EEG and audio were simultaneously recorded from four participants during ~10.7 hours of reading aloud. These recordings were then played to eight other participants, collecting ~21.6 hours of EEG during listening. This setup enables speech temporal and semantic alignment across the RA and PL modalities. ChineseEEG-2 includes EEG signals, precise audio, aligned semantic embeddings from pre-trained language models, and task labels. Together with ChineseEEG, this dataset supports joint semantic alignment learning across speaking, listening, and reading. It enables benchmarking of neural decoding algorithms and promotes brain-LLM alignment under multimodal language tasks, especially in Chinese. ChineseEEG-2 provides a benchmark dataset for next-generation neural semantic decoding.

  • 11 authors
·
Aug 5, 2025

A Cross-Modal Approach to Silent Speech with LLM-Enhanced Recognition

Silent Speech Interfaces (SSIs) offer a noninvasive alternative to brain-computer interfaces for soundless verbal communication. We introduce Multimodal Orofacial Neural Audio (MONA), a system that leverages cross-modal alignment through novel loss functions--cross-contrast (crossCon) and supervised temporal contrast (supTcon)--to train a multimodal model with a shared latent representation. This architecture enables the use of audio-only datasets like LibriSpeech to improve silent speech recognition. Additionally, our introduction of Large Language Model (LLM) Integrated Scoring Adjustment (LISA) significantly improves recognition accuracy. Together, MONA LISA reduces the state-of-the-art word error rate (WER) from 28.8% to 12.2% in the Gaddy (2020) benchmark dataset for silent speech on an open vocabulary. For vocal EMG recordings, our method improves the state-of-the-art from 23.3% to 3.7% WER. In the Brain-to-Text 2024 competition, LISA performs best, improving the top WER from 9.8% to 8.9%. To the best of our knowledge, this work represents the first instance where noninvasive silent speech recognition on an open vocabulary has cleared the threshold of 15% WER, demonstrating that SSIs can be a viable alternative to automatic speech recognition (ASR). Our work not only narrows the performance gap between silent and vocalized speech but also opens new possibilities in human-computer interaction, demonstrating the potential of cross-modal approaches in noisy and data-limited regimes.

  • 5 authors
·
Mar 1, 2024